Learn all about CoQ10

What is CoQ10?

Boost cell energy & heart health with CoQ10! This key nutrient, vital for energy & protecting cells from damage, declines with age & statin use.

Benefits of CoQ10

  • Supports the function of cell power centres ('mitochondria') and energy production throughout the body[ref]
"CoQ10 is key for cell energy and acts as a strong antioxidant, making it vital for heart health. Research strongly supports its use in heart failure, helping patients feel better and exercise more. The fact that statins lower CoQ10 and might cause muscle symptoms is important for the 10-15% of users affected. While not everyone on statins needs CoQ10, those with muscle issues often benefit. Since our natural CoQ10 levels drop with age as heart risks increase, it's worth considering. The 'ubiquinol' form is often absorbed better, especially for older adults who might struggle to convert the 'ubiquinone' form. For general health or statin support, 100-200mg daily is a good start, but higher doses are used for specific heart conditions under medical guidance."
- Dr. Peter H. Langsjoen, MD, FACC, Cardiologist and CoQ10 researcher at East Texas Medical Center (source)

How to use CoQ10

Dosage

For general health, 100-200 milligrams (mg) daily is common. For heart support, 200-300mg daily is often used. Higher doses (300-600mg) may be used for specific issues, but talk to a doctor first.

Timing

Take with a meal containing some fat for best absorption. If taking over 200mg, you can split the dose (e.g., morning and evening).

Notes

The ubiquinol form is usually absorbed better, especially if you're over 40. Softgels or oil-based capsules generally absorb better than powders or tablets because CoQ10 dissolves in fat. It usually takes 2-4 weeks to notice effects. Good brands state the form (ubiquinone or ubiquinol) and amount clearly.

Who should take CoQ10?

  • Adults over 40 wanting to support heart health and energy levels
  • People taking statin drugs (which can lower CoQ10 levels)
  • Those with heart disease risk factors (like high blood pressure, high cholesterol) seeking extra support
  • People noticing an energy decline related to aging
  • Individuals exposed to factors that cause cell damage ('oxidative stress')

How does CoQ10 work?

CoQ10 does two main things. First, it's vital for making energy inside the cell's power centres ('mitochondria'). It acts like a ferry, carrying tiny particles (electrons) through steps that turn food into cell fuel (ATP). This is crucial for organs that need lots of energy, like the heart. Without enough CoQ10, energy production drops. Second, in its active 'ubiquinol' form, CoQ10 is a powerful antioxidant that works in fatty areas. It protects cell walls, mitochondria, and fat carriers ('lipoproteins') from damage caused by harmful molecules ('free radicals'). It also helps 'recharge' vitamin E, another antioxidant. CoQ10 also affects how genes work, helps blood vessels relax, and may reduce inflammation. For people taking statins, CoQ10 supplements help replace what the drug prevents the body from making (statins block a pathway needed for both cholesterol and CoQ10 production).

Frequently asked questions

Natural sources of CoQ10

Foods contain CoQ10, but much less than supplements. The best sources are organ meats (especially heart), muscle meats (beef, pork), and fatty fish (sardines, mackerel). Plant sources like soybeans, peanuts, seeds, and broccoli have smaller amounts. Cooking, especially frying, can reduce CoQ10 levels. A typical diet provides only about 3-5 mg daily, whereas supplements often contain 100-300 mg. Your body also makes CoQ10, but this requires nutrients like B vitamins and Vitamin C. Production decreases with age or due to certain drugs (like statins) or health conditions. To significantly raise CoQ10 levels, supplements are much more effective than food alone.

Potential side effects & risks

Warnings

Talk to your doctor before using if pregnant or breastfeeding (limited safety data), have severe heart failure or liver disease, or take blood thinners. Tell your doctor you take CoQ10 before any surgery. Check labels for potential allergens (like soy).

Side effects

Generally very safe. Mild stomach upset (feeling sick, diarrhoea) is possible but not common. Rarely, headache, dizziness, or rash might occur. It could cause mild trouble sleeping if taken late; take it earlier in the day. May slightly lower blood sugar (check levels if you have diabetes).

Interactions

May increase the effect of blood pressure medicines (monitor BP). Very low risk of interacting with blood thinners like warfarin, but check with your doctor. Might affect some chemotherapy or thyroid medications (monitor).